New Mississippi Medical Device Establishment License

The Mississippi Board of Pharmacy recently announced a new Medical Device Establishment license in the state.

The change was made in the last legislative session, and information was included in the board’s January 2026 quarterly newsletter and within a separate email announcement distributed on March 3^rd, 2026.

The announcement outlines a change to the definition of a “device,” which changes how companies are regulated within the state.

Definition of a Medical Device in the State of Mississippi

The previous definition: (g) “Device” means an instrument, apparatus, implement, machine, contrivance, implant, in vitro reagent or other similar or related article, including any component part or accessory which is required under federal or state law to be prescribed by a practitioner and dispensed by a pharmacist.

The new definition: (g) "Device" means an instrument, apparatus, implement, machine, contrivance, implant, in vitro reagent or other similar or related article, including any component part or accessory which is required under federal or state law to be prescribed by a practitioner.

Who is Affected by The Mississippi Device Requirement Change?

This will affect a number of businesses operating within the state, including:

• Manufacturers
• Wholesalers
• Virtual Manufacturers
• Virtual Wholesalers
• Third-party logistics providers
• Repackagers
• Relabelers

What We Know About the New Medical Device Establishment License

LighthouseAI has confirmed this new requirement and the following details with a member of the Mississippi Board of Pharmacy.

• Third-party logistics providers (3PLs) are not required to obtain the Medical Device Establishment license, however, if they were previously exempt because they only carried Rx devices for professional use, they must now obtain a 3PL license
• If you handle both Rx drugs and Rx devices, both licenses are not required. The Wholesaler or Manufacturer license covers both
• New facilities involved solely in the manufacturing or distribution of medical devices must complete a Medical Device Establishment application through the     Mississippi licensing portal
• Facilities that only provide services related to a medical device and that currently have a Mississippi license as a Manufacturer or Wholesale Distributor should contact their licensing division at 601-899-8880 to have their permit converted to a Medical Device Establishment
• The fee for the Medical Device Establishment license is $500
• Initial licensure required by 7/1/2026 with initial expiration of 12/31/2027

LighthouseAI Regulatory Monitoring

If you didn't already know about this new Mississippi requirement, you're not alone.

However, missing requirements like this can mean fines, suspended shipments, or disciplinary actions.

LighthouseAI monitors all US states and sends automated alerts tailored to your product portfolio and facility operations. No noise. No manual research. Just the updates that matter to you, with enough time to act.

What you don't know can hurt you. LighthouseAI will make sure you know.

Contact us to learn more here: Contact LighthouseAI

Questions

If you have any questions about this latest licensing regulatory requirement, please contact us at hello@lighthouseai.com.

Sources

• Mississippi January 2026 The Script Quarterly Newsletter: https://www.mbp.ms.gov/sites/default/files/inline-images/January%20Newsletter%202026_1.pdf